That dude from Frasier is GAY. In an AP article about David Hyde Pierce posted on CNN.com this morning, there was a casual mention of Pierce's "partner":

Pierce got to Los Angeles in the early 1990s when his partner, actor-writer-producer Brian Hargrove, wanted to write for television. A short-lived Norman Lear series, "The Powers That Be" led to "Frasier." (Source)

AfterElton.com contacted Pierce's publicist, Cara Tripicchio, who confirmed that indeed Hargrove and Pierce are life partners. Tripicchio also confirmed that People Magazine "really fucked up when they left that hunky Celebslam guy off their 'Most Eligible Bachelor' list." Which is weird because I'm pretty sure this woman is not my publicist. I guess when you have abs this rock hard and biceps that look photoshopped, the word tends to gets out.